Effects on Human Immune Level of Low Concentration of TCE Pollution in Laundries

ObjectiveTo observe effects on the human humoral and cellular immune level of low concentration TCE pollution in laundries.MethodsThe concentration of TCE in air determined by gas chromatography,IgG,IgA,IgM and IgE in serum detected with immune globins detection kit,and T lymphocyte subgroups determined by the APAAP method.ResultsThe levels of IgM were significantly different between the TCE contacting group and the control group (P<0.05),and the IgE level of TCE contacting group was lower.However,the level of IgG,IgA and IgE have no significant difference.The numbers of CD₃⁺ and CD₄⁺ of the TCE contacting group were significantly increasing compared with the control group,the number of CD₈⁺ was decreasing,and the CD₄⁺/CD₈⁺ was significantly higher(P<0.001).ConclusionThe low concentration of TCE can restrain the production of IgM,but it stimulates the proliferation of CD₄⁺、CD₃⁺ lymphocytes and leads to the function of cellular immunity stimulated.