Pathogenic and Epidemiological Study on Acute and Sporadic Virose Hepatitis of Liuzhou City

Objective To investigate the formation of classified acute and sporadic viral hepatitis of Liuzhou city.Methods Acute-phase sera of 121 patients with acute sporadic virose hepatitis of Liuzhou city were detected for acute-phase markers of various hepatitis viruses by using an enzyme-linked immunoserbent assay(EIA).Eighteen patients' sera whose types couldn't be distinguished by serum were detected for HEV RNA by using a reverse transcription-nested plymerase chain reaction(RT-nPCR).Results Among the 121 patients with acute sporadic virose hepatitis,patients with HA,patients with HB and patients with HC were 10.7%,58.6% and 68.8%,respectively.Patients with HC and HB occuppied 0.8%,and HD patients,there was one patient who was simutaneously infected with HE respectively,the rate being 3.3%.There were 7 patients with hepatitis E.There were 7 positive patietns whose sera couldnot be classified among those who were detected for HEV RNA.There were 14 patients with hepatitis E all together,the rate being 11.6%,those whose sera couldnot be classified were 9.1%,pure anti-HGV positive patients were not detected.The analysis of risk factors showed that the exposure history of blood from patients with hepatitis A(30.8%) was higher than that of those with hepatitis B(21.1%) while intestines exposure history(94.3%) of patients with hepatitis B was higher than that of those with hepatitis A(92.3%).Conclusions Of acute virose hepatitises of Liuzhou city hepatitis B was the most(58.7%),HEV RNA positive patients were more(38.8%) among those whose sera couldn't be typed.There was a rising trend thathepatitis A was infected through blood and hepatitis B was infected through the alimentary canal.