Study on Apotosis of 293 Cells Induced by Cadmium Chloride

Objective To explain apoptosis induced by cadmium chloride in 293 cells in vitro.Methods 293 cells were exposed to 0,12.5,25.0,50.0μmol/L of CdCl₂ for various time period,to measure the apoptosis by DNA agarose electrophoresis and ELISA.Results CdCl₂ could induce apotosis of 293 cells in vitro at concentration of 12.50,25.00,50.00μmol/L.Different concentration of CdCl₂ could also cause reduction of cells survial associated with exposed doses and time and apoptosis.Conclusion Cadmium chloride coucld induce 293 cell apoptosis in vitro associated with exposed dose and time.