Effects of microwaves radiation on immune function in mice

  Objective   To sudy the effects of microwaves on immune functions in mice, and to understand the role of microwave radiation on immune function.

  Methods   Mice were decapitated to determine the following parameters: the content of immunoglobulin G(IgG)in serum, ANAE positive rate in lymphocyte of peripheral blood, the peritoneal macrophage phagocytic capacity(phagocytosis index and phagocytosis rate), thymus index and spleen index.

  Results   Experiment one: The contents of IgG in serum in 1 mW/cm² treatment groups were significant higher than that of control(P < 0.01), but lower than that of control in 15 mW/cm² treatment group(P < 0.01);The ANAE positive rates of lymphocytes from peripheral blood in every treatment group were decreased significantly compared with control(P < 0.01);A significant enhancement of peritoneal macrophage phagocytic capacity(pagocytosis rate)was obserbed in mice irradiated at 1 mW/cm² (P < 0.05);The spleen index in 15 mW/cm² treatment group were significant lower than that of control.Experiment two: The content of IgG in serum tended to increase in accompany with prolong of irradiative duration and showed significant difference (P < 0.01)compared with control at 21st day; microw aves with different duration irradiation could decrease the Peritoneal macrophage phagocytes capacity at 15^th and 21^st day compared with sham irradiation group, There was a significant increase in spleen index in microwave group compared with the false irradiated group at 9^th, 21^st days.

  Conclusion   1.Microw aves irradiation can affect the immune function obviously, including the changes of humoral immunity, cellular immunity and nonspecific immunity.2.There are different effects of microwaves irradiation on the immune function according to the different power density and different irraqdiative duration.