Observation of antagonism of Lxeis Sonchifolia Hance against respiratory virus

  Objective   To observe the antagonism against cell infected with respiratory virus of Lxeis Sonchifolia Hance.through cell culture and experiment in mice in vivo.

  Methods   Virus Cytopathogenic Effect(CP E)was used in vitro to measure half inhibitary concentration(IC₅₀), inhibitory concentration(MIC)and treat index(TI).Mouse influenzal viral preumonia experiment was carried out in vivo to observe the pulmonary pathologic change and calculate the pathologic rate and pathologic inhibition rate.

  Results   TI of respiratory influenzal virus H₃N₂, respiratory syncytial virus(RSV)and adenvirus (ADV-3)was 10, 32 and 16 respectively.The patholo gic inhibitive rate in differ ent dosage grops was higher than that of control group(P < 0.05).

  Conclusion   Lxeis Sonchifolia Hance has significant inhibitive effect on RIV-H₃N₂, RSV and ADV-3.