Effect of soybean isoflavones on antioxidant ability in ovariectomized rats

  Objective   To investigate the influenceo of soybean isoflavones(SI)to ovariectomized rats' antioxidant ability.

  Methods   After being ovariectomized, the 3-month old rats were divided into 2 groups randomly.They were supplememed with deionized water or SI solution by garage, The rats were sacrificed at the end of 13 weeks.The cerebral mitochondrial respiratory functions were assayed with Clark oxygen electrode.The levesl of malondialdelyde(MDA)and the activities of glutathione peroxidase(GSH2Px)were detrrmined.

  Results   In the group of SI, rate of respiratory control(RCR), ratio of ADP and oxygen(P/O)and ratio of A TP and quantity of protein(OPR)increased significantly; the level of MDA decreased and the activity of GSH2Px increased.

  Conclusion   The SI can enhance the ability of antioxidant in ovariectomized rats.