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CUI Xiaoyan, LUO Qiong, YANG Mingliang, . Effect of Lycium barbarum polysaccharides on growth of human cervical carcinoma Hela cell and cell apoptosis[J]. Chinese Journal of Public Health, 2006, 22(12): 1411-1412. DOI: 10.11847/zgggws2006-22-12-02
Citation: CUI Xiaoyan, LUO Qiong, YANG Mingliang, . Effect of Lycium barbarum polysaccharides on growth of human cervical carcinoma Hela cell and cell apoptosis[J]. Chinese Journal of Public Health, 2006, 22(12): 1411-1412. DOI: 10.11847/zgggws2006-22-12-02
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Effect of Lycium barbarum polysaccharides on growth of human cervical carcinoma Hela cell and cell apoptosis

    Abstract
  •   Objective   To investigate the cell growth and cell apoptosis of Lycium barbarum polysaccharides(LBP) treated on human cevical carcinoma Hela cell cultured in vitro.
      Methods   Hela cells were treated with different doses of LBP, the rate of cell growth was detected by using trypan blue exclusion staining, and taking MTT assay to analyze the inhibition of cell growth, then the rate of cell apoptosis was measured by flow cytometry.
      Results   LBP could increasingly inhibit the growth of cervical carcinoma Hela cell line with dose2effect.The biggest inhibition rate was up to 96.85% in those treated with LBP, and the apoptosis rate was 36.8%.
      Conclusion   LBP could inhibit the growth of Hela cell line in vitro, and the mechanism might be related to the influence of LBP in the cell cycle and the cell apoptosis induced by LBP.
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