Association between diet and esophageal lesions in Feicheng city

Objective To invest igate the association of staple food,non-staple food,vegetables and their nutr ient elements of esophagitis,esophageal hyperplasia and early cancer.Methods In a high esophageal cancer incidence community of Feicheng city,a cohort of 3304 residents aged from 40 to 69 were examined for the esophageal lesions.The people with normal esophageal mucosa determined by gastric endosco pe ser ved as controls,and the 3 disease groups respectively consisted of patients with esophag itis,esophag eal hy perplasia and early cancer diagnosed by staining endoscope and pathogenic examination.Multinomial regression was used to determine the association between diet and esophageal lesions,and OR was used as the association indicator.Results Meat increased the risk of early cancer,but soybean,fish,oil,celery,eggplant,kidney bean,green pepper,fat,crude fibre,ash and calcium decreased the risk;wheat,oil and heat were the risk factors for esophageal hyper plasia,but leek and lettuce had protective effect against it;Oil and heat were the risk factors for esophagitis.Conclusion Diet and its nutrient elements are closely associated with eso phag eal cancer and precancerous lesions in high incidence ar eas of esophageal cancer.