Multi-metabolic disorders and metabolic syndrome in people with normal body mass index

ObjectiveTo study the prevalence of multi-metabolic disorders and metabolic syndrome in people with normal body mass index(BMI).MethodsSubjects were recruited from the project of the multiple metabolic disorders and metabolic syndrome prevention cohort study in Jiangsu province,in which 4 251(male 2 003,female 2 248)were selected into this study according to the including criteria.The National Cholesterol Education Program Adult Treatment PanelⅢ Asian criteria was used to define the metabolic syndrome,and the subjects were divided into 4 groups to compute the prevalence and OR of metabolic syndrome with BMI.ResultsThe total prevalence of metabolic syndrome was 12.66% (male 7.69%,female 17.08%)in 4 251 subjects.With the BMI raised,the prevalence in male increased from 2.58% to 12.54%,and from 6.33% to 30.50% in female,P<0.001 in trend test.The Logistic regression analysis,after controlling the factors of age, smoke,alcohol,habitation,education,marriage,income and total cholesterol,showed the OR for the metabo lic syndrome was 2.23 in men with BMI 20.71~22.16 kg/m 2,3.30 for men with BMI 22.17~23.49 kg/m² and 6.19 for men with BMI 23.50~24.99 kg/m² respectively,compared with men with BMI 18.50~20.70 kg/m².The cor responding ORs in women were 1.93,3.97 and 7.77.Do the same after Removing WC.The ORs for men was 2.27,3.46 and 5.17,the ORs for women was 1.39,2.36 and 2.59,Pvalue for trend test was P<0.001.ConclusionThere was also a high prev alence of mult imetabolic disorders and metabolic syndrome in people with normal body mass index,WC may has a stronger relationship with metabolic syndrome than BMI.