Effect of Elaeagnus bockii Diels on cell immunity function of mice with tumor
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Graphical Abstract
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Abstract
Objective To study the effect of Elaeagnus bockii Diels on cytokine of mice with tumor.Methods The amount of interleukin-2(IL-2)and in terferon(IFN)was tested with ELISA and the amount of tumornecrosis factor (TNF-α)was determined with MTT.Results The secretion of IL-2,IFN-γ and TNF-α in mice of Elaeagnus bockii Diels group and Elaeagnus bockii Diels+cyclopho sphamidecy(CY)group was obviously higher than that of model group and CY group(P<0.01).The Elaeagnus bockii Diels corrected Thelper I cells/Thelper 2 cells(Th1/Th2)drift phenomenon of the mice and kept the superiority state of Th1.Conclusion The Elaeagnus bockii Diels increases IL-2,IFN-γ and TNF-α,and promotes cell mimunity function of the mice with tumor.
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