Familial and occupational factors and primary lung cancer：a case-control study

ObjectiveTo investigate the family history and occupational factors related to primary lung cancer and to provide scientific basis for the prevention of primary lung cancer.MethodsA 1:1 matched case-control study was carried out among 200 cases and 200 controls in general hospitals in Dalian city.The main contents of the investigation included general health,occupational exposure,disease history,and family history of cancer.Data were analyzed with Chi-square test and the conditional logistic regression with SPSS 13.0 and SAS 8.2.ResultsThe results indicated that occupational hazards expoure increased the risk of primary lung cancer(odds ratio=9.625,95% confidence interval:4 647-19.934). Multivariate logistic regression analyeses showed that occupational hazardous exposure,thoracic x-ray examination and familial cancer history were risk factors of primary lung cancer.ConclusionThe incidence of lung cancer is related to many kinds of factors including occupational exposure and family history of cancer.