Environment risk factors of stomach cancer among Han people in Nanjing:a case-control study

Data of 476 new cases of gastric cancer and 476 controls were collected from April 2008 to October 2011 with a questionnaire survey.Potential risk factors were analyzed with logistic regression model and odds ratio(OR) and 95% confidence interval(CI) were calculated.Results The ratios of history of digestive system disease,family history of digestive system disease,family history of tumor,the history of poisonous substances exposure,smoking,alcohol drinking,preference of taking pickled food,irregular diet habit,engorgement,high fresh fruit consumption,high milk consumption,high smoked and fried food consumption,and depression in case group were 33.61%,18.07%,22.06%,22.48%,48.74%,71.01%,22.48%,20.17%,7.98%,59.03%,67.44%,22.06%,and 62.39% and the ratios in the controls were 19.12%,7.56%,8.19%,13.66%,40.13%,53.78%,7.77%,7.56%,1.68%,79.83%,81.72%,9.24%,and 19.54%,respectively.The differences in the ratios between the case and control groups were statistically significant (P<0.05 for all).The multivariate logistic regression analyses showed that the history of digestive system disease,family tumor history,irregular diet habit,high smoked and fried food consumption,and depression were risk factors of gastric cancer.High fresh fruit consumption was a protective factor for stomach cancer.Conclusion The family history of digestive system disease,family tumor history,smoked and fried food consumption,irregular diet habit,depression,and high fresh fruit consumption were impact factors of gastric cancer in the Han residents of Nanjing.