Distribution of pathogenic bacteria causing lower respiratory tract infections among neurology inpatients

Objective To study distributive characteristics of pathogenic bacteria causing lower respiratory tract infection in neurology inpatients and to provide evidences for promoting rational drug use.Methods Two third-grade class-A hospitals were selected with convenience sampling in Dalian city of Liaoning province; then 1 600 neurology inpatients with lower respiratory tract infections during hospitalization between January 1st,2014 through December 31st,2015 were selected randomly and their medical records were extracted and analyzed.Results Of the 2 109 strains of pathogenic bacteria totally isolated from the inpatients,1 372 and 624 were gram-negative and gram-positive bacteria and 113 were fungi,with 362 (17.16% of all the isolates) Klebsiella pneumoniae strains,302 Staphylococcus aureus (14.32%),and 113 Candida albicans (2.66%),respectively.Drug resistance was performed for 71.85% (217/302) and 78.73% (285/362) of the isolated Staphylococcus aureus and Klebsiella pneumoniae strains; no Staphylococcus aureus strains resistant to vancomycin were detected and only 3.16% of Klebsiella pneumoniae strains were resistant to meropenem.Conclusion Pathogen surveillance and drug resistance test for isolated pathogens among inpatients may promote rational drug use and nosocomial infection prevention.