Objective To observe the changes of serum cortisol supplemented L-arg inine under heat stress in rats, and the mechanism of protect effect of L-aginine on thymus gland was investigated.
Methods SD youthhood rats were diveded into three groups randomlly which were control group, L-arginine group and a group fed on VE.The concentration of serum cortisol under room temperature of 0 hour, 4 hours and 78 hous respectively after heat stress was determined.
Results The concentration of serum cortisol raised obviously in all groups after heat stress.The concentraiton of serum cortisol was the highest after 41h of heat stress, while those of group of supplemented L-arginine could relieve thmus gland and spleen acute atrophy under heat stress.
Conclusion Appropriate L-Arginine can inhibit the significant increase of the serum cortisol concentration and decrease thyums gland and spleen index under heat stress, and it has obvious protective effect on the hea-t stressed thymus gland, and enhances immunity of body as well.
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