Effect of tomato juice on DNA damage of human prostate carcinoma cell

  Objective   To study the effect of tomato juice on the growth of human prostate carcinoma cell (PC-3).

  Methods   PC-3 cell was treated by the tomato juice with 40, 80, 120 l/ml for 48 h; Single cell gel electro phoresis(SCGE) assay was applied to determine the DNA damage of PC-3 cell.

  Results   Tomato juice could induce the breakage of DNA strand of PC-3 cell; Rate of DNA tail and the tail length of experimental groups were significantly higher than that of control group, with very statistical significance.

  Conclusion   Tomato juice could lead to DNA damage of PC-3 cell.