Bacteriostasis effect of isothiazolinone derivatives and its application in detergent antisepticising

  Objective   To study the bacteriostasis effect of one of the isothiazolinone derivatives KF-88 and observe its bacteriostasis efficacy in detergent.

  Methods   To use nutrition broth dilution method to determine its minimal inhibitory concentration (MIC) to straphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger, and complete the simulated on-the-spot tests.

  Results   The MIC of KF-88 to straphylococcus aureus and Candida albicans was 0.0016‰; the MIC to Escherichia coli and aspergillus niger was 0.03‰; KF-88 could restrain straphylococcus aureus to propagate in detergent when its concentration in detergent was 1‰.

  Conclusion   The isothiazolinone derivatives had very strong bacteriostasis efficacy for bacteria, mildew and yeast, they have valuable application prospect in detergent industry and other industry field.