Expressions study of c-fos protein of fetal brain hippocampus from iodine and selenium as well as iodine deficiency and selenium abundanc regions

  Objective   To study the relation between selenium position and expression of c-fos protein of fetal brain neurons.

  Methods   To collect 51 cases umbilical cord blood from three different seleium position regions(Ziyang county, Lintong county), assaying the Se, I position, then to collect 20 cases of abortion fetal brains fr om those regions, and exame the expressions of c-fos protein in fetal brains hippocampus by immuno histo chemistry.

  Results   There were no difference among three regions with iodine, there were difference with selenium among three regions, and selenium level were hig her in Ziyang, lower in Yijun, the expressions of c-fos protein were higher in Ziyang and there were differ ence between Ziyang and Yijun.

  Conclusion   Selenium position might affect the expression of c-fos protein of fetal brain and the development of neuron system and intellecutal.