Research on effect of air pollution on microecology of rat respiratory tract

  Objective   To explore the mechanism of respiratory tract symptom and health effect caused by air pollution and provide the theory basis for preventing air polrlution.

  Methods   Animal model of wistar rat was made and rats were poisoned by imitating real air pollution, which included high, middle, lower air pollutant concentration.Bacteria flora of pharynx of rat was tested qualitatively, dynamically and position was measured.

  Results   Microecology of pharynx in polluted rats appeared change.Klebsiella pneumoniae etc.pathogenic bacteria increased and anaerobe bacteria decreased(P < 0.05).The number of anaerobe bacteria and whole bacteria declined with polluted time extending.The density of pharynx bacteria flora fluctuated in a certain range and did not change with pollutant concentration.

  Conclusion   Air pollution couldlead to the change of respiratory tract bacteria flora, damage the micro-environment, make normal bacteria of pharynx decreased and pathogenic bacteria planted, and it was an important factor to increase incidence of respiratory disease.