Epidemiological analysis on guillain-barre syndrome(GBS) among children aged 0-14 years in Liaoning province

  Objective   To analyze the incidence of Guillain-Barre Syndrome(GBS)and its characteristics in childhood(aged 0 -14 years old)in Liaoning province and the latent risk factors.

  Methods   To investigate 218 GBS cases reported by hospitals and analyze the information statistically.

  Results   The average annual crude incidence reported was 0.65 per 100 000.The GBS case mortality was 4.1 percent.The residual paralysis was 55.4 percent.The positive isolation of enteroviruses was 7.3 percent.Study showed that the incidence varied in different season.The incidence in summer was 1.3 times higher than that in winter(0.93/100 000 vs 0.4/100 000, P < 0.05).

  Conclusion   The infection of enteroviruses and taking oral polio vaccines(OPV)may be the latent risk factors.The residual paralysis was so high that 55.4 percent of GBS cases could not recover completely.Others papers related to this subject reported that the residual paralysis was 15 percent.There was significant differnece between them(P < 0.05).It should be noticed greatly by clinic doctors, staff of EPI and parents of children.