Study On Antibody Dependent Immunization Enhancement and Immunology Strategy of Type I Inactivated Vaccine against EHF Prepared from Tissure of Mongolian Gerbils Kidney
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Graphical Abstract
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Abstract
Obijective:This article reported two problems that attached importance to us when the Type I inactivated vaccines against EHF were applied.The first was danger occurring immunization pathology.The result indicated that the second infection was existential by the research on the cases of inoculated group and testing double serum EHF.V.IgG antibody of the inoculated population before and after the epidemic peak.No ADE was found among the inoculated population.The second was immunity strategy.We offered some suggestion on the type of vaccine,the control of vaccine quality,the simplification of immunity program and the inoculated population,respectively.
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