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玉米紫色植株花色苷色素抗脂质过氧化作用

Function of anthocyanin pigment from maize purple plant to resist lipid peroxidation

  • 摘要: 目的 探讨玉米紫色植株色素抗脂质过氧化的作用。方法 体外实验测定玉米紫色植株花色苷色素在Fe2+引发的卵磷脂脂质体体系中抗氧化活性。体内实验,取50只小鼠随机分成5组,分别给予溶媒和不同剂量的色素,然后采用溴代苯致实验性肝损伤,测定肝匀浆的丙二醛含量。结果 在由Fe2+引发的卵磷脂脂质体体系中玉米紫色植株色素对脂质过氧化有明显的抑制作用,抑制率随样品的浓度增高而增大,并且明显优于抗坏血酸。在溴代苯致小鼠实验性肝损伤模型实验中,中、高剂量组的丙二醛含量均低于损伤模型组。低剂量组和损伤模型组比较丙二醛含量差异无统计学意义。结论 玉米紫色植株色素具有较强的抗脂质过氧化作用。

     

    Abstract: Objective The effects of anthocyanin pigment from maize purple plant on resisting lipid peroxidation were investigated.Methods The inhibition of anthocanin pigment from maize purple plant was examined in vitro that autcoxudation of lecithin liposome system induced by Fe2+ .50 mice were randomly divided into 5 groups.Vehicle and different dose anthocyanin pigment from maize purple plant were given respectively,and then experimental injury of mice liver was induced to make use of bromobenzene and the content of MDA was determined in liver homogenate.Results The inhibition rates of an2 thocyanin pigment from maize purple plant on linoleic acid oxidation was higher that of ascorbic ascorbic acids.The content of MDA in homogenate in middle and high dose of pigment were significantly lower than that in low dose and the injured control group.There were no significat differences in the content of MDA in homogenate between low dose group and injury control group.Conclusion The anthocyanin pigment from maize purple planthave the capability to resist lipid peroxide.

     

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