Abstract: Objective To understand the prevalence of food poisoning in Guangzhou city and to provide scientific evidence for the prevention of food poison ing.Methods The analysis was conducted for the number of cases,the number of suffered individuals,the distribution of the time and place,and the causes of food paisoning occurred in the city from 1997 to 2007.Results To tally 462 cases of food poisoning occurred with 8682 poisoning cases and 37 fatalities.The average annual morbidity was 10.70/100000.The incidence rate of poisoning was higher in the second and the third quarter of the year and the mortality of food poisoning was higher in the first quarter of they ear.The collective can teens were the main places o f the occurrence of food poisoning and meat,meat products,fruits,and vegetables were the major food contaminated.Conclusion The key point to prevent food poison ing is controlling the contam inations of meat,meat proiduct,fruit,and vegetable in the highinc idence sea son.