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张伟, 艾木拉江·买买提艾力, 蔡志华, 孙玉萍. 健康体检人群尿酸水平与糖脂代谢关系[J]. 中国公共卫生, 2011, 27(5): 643-645. DOI: 10.11847/zgggws-2011-27-05-55
引用本文: 张伟, 艾木拉江·买买提艾力, 蔡志华, 孙玉萍. 健康体检人群尿酸水平与糖脂代谢关系[J]. 中国公共卫生, 2011, 27(5): 643-645. DOI: 10.11847/zgggws-2011-27-05-55
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ZHANG Wei, CAI ZHi-hua, . Relationship between serum uric acid and metabolism of blood sugar and lipid in healthy people[J]. Chinese Journal of Public Health, 2011, 27(5): 643-645. DOI: 10.11847/zgggws-2011-27-05-55
Citation: ZHANG Wei, CAI ZHi-hua, . Relationship between serum uric acid and metabolism of blood sugar and lipid in healthy people[J]. Chinese Journal of Public Health, 2011, 27(5): 643-645. DOI: 10.11847/zgggws-2011-27-05-55
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健康体检人群尿酸水平与糖脂代谢关系

Relationship between serum uric acid and metabolism of blood sugar and lipid in healthy people

    摘要
  • 摘要: 目的 分析健康体检人群尿酸与糖脂代谢的关系。方法 收集2009年10月在新疆医科大学第一附属医院进行健康体检人员的血液样本1 236份,采用日立7060全自动生化分析仪检测血液生化指标,血尿酸浓度检测采用尿酸酶法。结果 男性载脂蛋白A(ApoA)为(1.23±0.139)g/L,女性为(1.32±0.150)g/L;高密度脂蛋白(HDL-C)男性为(1.30±0.23)mmol/L,女性为(1.52±0.338)mmol/L,男性低于女性,而其他指标均高于女性(P<0.05);汉族ApoA、尿素氮(BUN)、肌酐(SCR)、甘油三酯(TG)、HDL-C高于维吾尔族,而维吾尔族载脂蛋白B(ApoB)、总胆固醇(TC)、空腹血糖(FBS)、低密度脂蛋白(LDL-C)高于汉族,统计学分析ApoA、ApoB、TC和LDL-C差异有统计学意义(P<0.05);高尿酸组除了ApoA和FBS外,其他指标均高于正常组(P<0.05);随尿酸水平增高,ApoA和HDL-C有降低的趋势外,其他脂代谢指标均增高,差异有统计学意义(P<0.05);但是尿酸对血糖影响不大;除了低高密度脂蛋白血症,其他代谢紊乱均随尿酸水平增高。结论 不同民族和性别各种糖脂代谢指标不同,随着尿酸水平的增高,各项血液生化指标向对人体健康不利的方向发生变化,脂代谢紊乱发生率增加。

     

    Abstract: Objective To analyze there lation ship between serumuric acid and metabolism of blood sugar and lipid in healthy people.Methods The blood samples of 1 236 healthy people were collected and analyzed for uricacid,glycerin,total chole sterol(TC),high density lipoprote in chole sterol(HDL-C),and low density lipoprote in cholestero l(LDL-C).Results Most of the blood biochemical indicators of the males were higher than those of the females with significant difference(P<0.05)exceptapo lipoprotein A(A poA)and HDL-C.In Han subjects,the A poA,blood urea nitrogen(BUN),TG,HDL-C were higher than in Uygur subjects.But in the Uygu,rthe A poB,TC,fasting blood sugar(FBS),LDL-C were higher than in the Han(P<0.05).Other blood bio-chemical indicators in hyperuricemia group were higher than those of normal group and the indicators increased with the increase of serumuric acid except A poA and HDL-C(P<0.05).The prevalences of the diseases increased with the increase of uricacid(P<0.05).Conclusion The blood biochemical indicators are different bewteen sex and ethnic groups and increase with the increment of serumuric acid level.

     

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