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血浆同型半胱氨酸水平与脑卒中关系研究进展

张鸥 刘洋 蒙航娟 丛树艳

张鸥, 刘洋, 蒙航娟, 丛树艳. 血浆同型半胱氨酸水平与脑卒中关系研究进展[J]. 中国公共卫生, 2021, 37(12): 1840-1844. doi: 10.11847/zgggws1127767
引用本文: 张鸥, 刘洋, 蒙航娟, 丛树艳. 血浆同型半胱氨酸水平与脑卒中关系研究进展[J]. 中国公共卫生, 2021, 37(12): 1840-1844. doi: 10.11847/zgggws1127767
ZHANG Ou, LIU Yang, MENG Hang-juan, CONG Shu-yan. Progress in researches on plasma homocysteine level and stroke: a review[J]. Chinese Journal of Public Health, 2021, 37(12): 1840-1844. doi: 10.11847/zgggws1127767
Citation: ZHANG Ou, LIU Yang, MENG Hang-juan, CONG Shu-yan. Progress in researches on plasma homocysteine level and stroke: a review[J]. Chinese Journal of Public Health, 2021, 37(12): 1840-1844. doi: 10.11847/zgggws1127767

血浆同型半胱氨酸水平与脑卒中关系研究进展

doi: 10.11847/zgggws1127767
详细信息
    作者简介:

    张鸥(1989 – ),女,山西绛县人,医师,硕士,研究方向:神经系统疾病的康复治疗

    通讯作者:

    丛树艳,E-mail:congshuyan@Hotmail.com

  • 中图分类号: R 743

Progress in researches on plasma homocysteine level and stroke: a review

  • 摘要: 同型半胱氨酸作为脑卒中的独立危险因素,与卒中发病率、复发率及预后均密切相关,在不同的卒中亚型中水平各有差异,致病机制主要涉及血管内皮损伤、平滑肌细胞增生、凝血及脂肪代谢异常等多个方面。同型半胱氨酸水平受基因型及代谢、年龄、性别、药物等多种因素影响,补充B族维生素及叶酸能显著降低同型半胱氨酸水平,降低高危人群的同型半胱氨酸水平对脑血管病的二级预防具有重要意义。本文针对同型半胱氨酸水平与脑卒中及其亚型、严重程度的相关性,在脑卒中发病机制中的作用以及治疗现状等方面进行综述,旨在为脑卒中临床预防及治疗提供参考。
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出版历程
  • 收稿日期:  2020-01-05
  • 网络出版日期:  2021-08-12
  • 刊出日期:  2021-12-13

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