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陈冯梅, 郭志荣, 海波, 骆文书, 胡晓抒, 武鸣. 体质指数、腰围、腰臀比和腰高比对高血压发病影响前瞻性队列研究[J]. 中国公共卫生, 2021, 37(12): 1774-1777. DOI: 10.11847/zgggws1128795
引用本文: 陈冯梅, 郭志荣, 海波, 骆文书, 胡晓抒, 武鸣. 体质指数、腰围、腰臀比和腰高比对高血压发病影响前瞻性队列研究[J]. 中国公共卫生, 2021, 37(12): 1774-1777. DOI: 10.11847/zgggws1128795
CHEN Feng-mei, GUO Zhi-rong, HAI Bo, . Associations of waist circumference, waist-hip ratio, waist-height ratio, and body mass index with hypertension incidence among 35 – 74 years old residents in Jiangsu province: a prospective cohort study[J]. Chinese Journal of Public Health, 2021, 37(12): 1774-1777. DOI: 10.11847/zgggws1128795
Citation: CHEN Feng-mei, GUO Zhi-rong, HAI Bo, . Associations of waist circumference, waist-hip ratio, waist-height ratio, and body mass index with hypertension incidence among 35 – 74 years old residents in Jiangsu province: a prospective cohort study[J]. Chinese Journal of Public Health, 2021, 37(12): 1774-1777. DOI: 10.11847/zgggws1128795

体质指数、腰围、腰臀比和腰高比对高血压发病影响前瞻性队列研究

Associations of waist circumference, waist-hip ratio, waist-height ratio, and body mass index with hypertension incidence among 35 – 74 years old residents in Jiangsu province: a prospective cohort study

  • 摘要:
      目的  探讨体质指数(BMI)、腰围(WC)、腰臀比(WHR)和腰高比(WHtR)等脂肪指标对高血压发病的影响。
      方法  采用前瞻性队列研究方法,于1999年4月对在江苏省抽取的3个城市社区和9个自然村共8865名35~74岁城乡居民进行基线调查,随后分别于2002年1月 — 2003年8月和2006年3月 — 2007年11月对基线调查满2年和5年的城乡居民进行随访,将其中参与2次随访且基线调查和首次随访中无高血压、糖尿病、心血管疾病和空腹血糖 ≥ 5.6 mmol/L的2531名城乡居民作为研究对象进行问卷调查和体格检查,分析WC、BMI、WHR和WHtR对高血压发病的影响。
      结果  江苏省2531名城乡居民2次随访间隔中位数为3.8年,此期间新发高血压469例,高血压发病率为18.53 %;多因素Cox比例风险回归分析结果显示,在调整了性别、年龄、文化程度、职业、家庭人均年收入、吸烟情况和饮酒情况等混杂因素后,BMI第三四分位数和最高四分位数者高血压发病风险分别为最低四分位数者的1.46和2.42倍,WC第三四分位数和最高四分位数者高血压发病风险分别为最低四分位数者的1.63和2.51倍,WHR第三四分位数和最高四分位数者高血压发病风险分别为最低四分位数者的1.70和2.62倍,WHtR第三四分位数和最高四分位数者高血压发病风险分别为最低四分位数者的1.91和2.08倍;BMI和WC对高血压发病联合作用的多因素Cox比例风险回归分析结果显示,在调整了性别、年龄、文化程度、职业、家庭人均年收入、吸烟情况和饮酒情况等混杂因素后,BMI最高三分位数合并WC第二三分位数和最高三分位数者高血压发病风险分别为BMI最低三分位数合并WC最低三分位数者的1.86和2.55倍。
      结论  WC、BMI、WHR和WHtR等脂肪指标较高可增加高血压的发病风险。

     

    Abstract:
      Objective  To explore effects of body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and waist to height ratio (WHtR) on hypertension incidence among adult community population.
      Methods  During April 1999 in Jiangsu province, a baseline survey was conducted among 8 865 residents aged 35 – 74 years in three urban communities and nine natural villages and then two follow-up studies were carried out among 4 582 and 3 847 residents 2 and 5 years after the baseline survey. Finally, physical examination and questionnaire interview were performed among 2 531 residents being followed-up 2 or 5 years later and without hypertension, diabetes, cardiovascular diseases and high fasting blood glucose (≥ 5.6 mmol/L) at the baseline survey. Multivariate Cox proportional hazard regression analysis was adopted to analyze the effects of WC, BMI, WHR and WHtR on hypertension incidence.
      Results  Among the 2 531 participants with a median follow-up interval of 3.8 years, 469 new hypertension were diagnosed by the end of follow-up and the hypertension incidence rate was 18.53%. After adjusting for gender, age, education, occupation, family annual income per capita, smoking and alcohol drinking, significantly higher hypertension risks were estimated for the participants with the third and the highest quartile value of BMI (hazard risk HR = 1.46 and 2.42), WC (HR = 1.63 and 2.51), WHR (HR = 1.70 and 2.62), and WHtR (HR = 1.63 and 2.62) compared to the participants with the lowest quartile value of the four indicators, respectively; furthermore, the hypertension risk was significantly higher for the participants with the highest tertile value of BMI and the second or the highest tertile values of WC (HR = 1.86 and 2.55) in comparison with the participants with the lowest tertile value of BMI and WC.
      Conclusion  High somatotype indexes including WC, BMI, WHR and WHtR are associated with increased risk of hypertension incidence among adult community residents.

     

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