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史卫卫, 寻鲁宁, 曹亚景, 王伟, 崔泽, 路笑颖, 孙纪新. 河北省居民2015 — 2018年脑梗死流行特征分析及时间序列预测[J]. 中国公共卫生, 2021, 37(12): 1800-1804. DOI: 10.11847/zgggws1131022
引用本文: 史卫卫, 寻鲁宁, 曹亚景, 王伟, 崔泽, 路笑颖, 孙纪新. 河北省居民2015 — 2018年脑梗死流行特征分析及时间序列预测[J]. 中国公共卫生, 2021, 37(12): 1800-1804. DOI: 10.11847/zgggws1131022
SHI Wei-wei, XUN Lu-ning, CAO Ya-jing, . Prevalence characteristics of cerebral infarction among residents in Hebei province, 2015 – 2018: a time series analysis[J]. Chinese Journal of Public Health, 2021, 37(12): 1800-1804. DOI: 10.11847/zgggws1131022
Citation: SHI Wei-wei, XUN Lu-ning, CAO Ya-jing, . Prevalence characteristics of cerebral infarction among residents in Hebei province, 2015 – 2018: a time series analysis[J]. Chinese Journal of Public Health, 2021, 37(12): 1800-1804. DOI: 10.11847/zgggws1131022

河北省居民2015 — 2018年脑梗死流行特征分析及时间序列预测

Prevalence characteristics of cerebral infarction among residents in Hebei province, 2015 – 2018: a time series analysis

  • 摘要:
      目的  了解河北省居民2015 — 2018年脑梗死流行特征,探索时间序列模型在脑梗死发病率预测中的应用,为今后脑梗死防控工作提供技术支持。
      方法  收集河北省2015年1月1日 — 2018年12月31日慢性非传染性疾病监测系统中全省18个脑梗死事件监测点报告的居民脑梗死发病数据对河北省居民2015 — 2018年脑梗死流行特征和变化趋势进行分析,同时建立时间序列模型对河北省居民2019年全年及各月份脑梗死发病率进行预测。
      结果  河北省居民2015 — 2018年脑梗死年均发病率为311.73/10万,其中2015、2016、2017和2018年脑梗死发病率分别为283.22/10万、296.36/10万、322.93/10万和342.55/10万,脑梗死发病率随年份增长呈上升趋势(χ2趋势 = 624.353,P < 0.001);男性居民脑梗死发病率为348.81/10万,高于女性居民脑梗死发病率的273.60/10万,差异有统计学意义(χ2 = 1 680.967,P < 0.001);年龄 < 35、35~44、45~54、55~64、65~74、75~84和 ≥ 85岁居民脑梗死发病率分别为2.58/10万、48.96/10万、263.21/10万、650.61/10万、1641.77/10万、2083.59/10万和3000.88/10万,不同年龄居民脑梗死发病率差异有统计学意义(χ2 = 381 051.465,P < 0.001);建立的最佳拟合模型为ARIMA(0,1,1)(2,1,0)12,最小信息量准则(AIC)为214.480,贝叶斯信息准则(BIC)为220.698,残差序列为白噪声序列(P > 0.05),模型参数显著非零(P < 0.05),均方根误差(RMSE)、平均绝对误差(MAE)和平均绝对百分比误差(MAPE)分别为2.97、1.62和7.55 %,模型构建科学有效;预测2019年河北省居民全年脑梗死发病率为362.46/10万,较往年升高,1 — 12月发病率在23.62/10万~33.33/10万,与历年月发病趋势变化基本相符。
      结论  河北省居民2015 — 2018年脑梗死发病率仍处于较高水平,且呈逐年上升趋势,男性和老年群体为脑梗死的高危人群,时间序列模型在脑梗死的防治和干预中能够提供有效的技术支持。

     

    Abstract:
      Objective   To examine prevalence characteristics of cerebral infarction (CI) among residents in Hebei province from 2015 to 2018, and to explore the application of time series model in the prediction of CI incidence for the prevention and control of the disease.
      Methods   From National Chronic Non-Communicable Disease Surveillance System, we collected the data on registered cerebral infarction incidents in 18 surveillance points in Hebei province from January 1, 2015 through December 31, 2018. The prevalence characteristics of CI and its changing trend were analyzed and a time series model was established to predict annual and monthly incidence rate of CI in 2019.
      Results  During the 4-year period in the province, the average annual CI incidence rate were 311.73/100 000, with the yearly incidence rate of 283.22, 296.36, 322.93, and 342.55 per 100 000 for the year from 2015 to 2018 and a significantly increasing trend (χ2 = 624.353, P < 0.001). The CI incidence rate in the male residents were significantly higher than that in the female residents (348.81/100 000 vs. 273.60/100 000, χ2 = 1 680.960; P < 0.05). The age-specific CI incidence rate was significantly different among various age groups, with the rate of 2.58, 48.96, 263.21, 650.61, 1 641.77, 2 083.59, and 3 000.88 per 100 000 for the residents aged < 35, 35 – 44, 45 – 54, 55 – 64, 65 – 74, 75 – 84, and ≥ 85 years, respectively (χ2 = 381 051.465, P < 0.001). The established best fitted model was ARIMA (autoregressive integrated moving average) (0, 1, 1)(2, 1, 0)12; the model's residual sequence was white noise sequence (P > 0.05); and the parameters for the established model were as following: Akaike information criterion (AIC) = 214.480, Bayesian information criterion (BIC) = 220.698, root mean square error (RMSE) = 2.97, mean absolute error (MAE) =1.62, and mean absolute percentage error (MAPE) = 7.55%. Based on the model, the predicted yearly CI incidence rate was 362.46/100 000 for the residents in 2019, which was higher than that in previous years; the predicted monthly CI incidence rates ranged between 23.62/100 000 and 33.33/100 000 and the variation of the rates for the year of 2019 was similar to that in previous years.
      Conclusion   The incidence rate of cerebral infarction was at a high level and increased yearly during 2015 – 2018 among residents in Hebei province; the incidence rate was relatively higher in the male and the elderly residents. Time series model can be used to predicate the incidence rate for the prevention and control of cerebral infarction.

     

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