Abstract: To study the people's health status in endemic fiurosis areas and suggest a new index-quality adjusted life expectancy(QALE) which is used to measure quality of life and living time together.The quality of life of dental flurosis patients and skeleton flurosis patients was investigated by designed questionnaires.The index of quality of life(IQL) was calculated for each patient by weighting method and then the life expectancy was adjusted by IQL and endemic flurosis prevalence according to life table theory.The QALEs of 0-year-old were respectively 65.2657,64.1764,63.4486,63.1624 in areas with fluorine concentration in drinkable water being1.0～2.0mg/L,2.0～4.0 mg/L,4.0～7.0 mg/L and over 7.0 mg/L.The higher the prevalence of endemic flurosis,the shorter the QALE.QALE can be used to value and compare health status and medical level among countries or areas as an index measuring quality of life and living time together.