Abstract: ObjectiveTo explore the change of car diovascular and cerebrovascular disease factors in children of different nutritional conditions.Methods317 health children aged 7~11 years were selected randotmly from 4 primary schools in Beijing.Anthropometry was carr ied out for all of them.Fasting insulin and lipids were measured and family history of the cardiovascular and cerebrovascular disease was recorded for them.Results13.9% of the children was malnutrition(defined as weight for height <90% of the ideal weight).24.0% of the children was overweight(defined as weight for height>1.0% of the ideal weight).The prevalence of the car diovascular and ceredrovescular disease was significantly higher in family members of malnur ition and overweight children compared with ideal weight children(59.5% and 45.7% Vs 33.9% P<0.01).The over weight children showed higher age and sex-adjusted mean vaiue of blood pressure,fasLing insulin,triglyceride,and lower value of HDL/LDL,apoA/apoB than nonoverw eight(P<0.01)and higher value of cholesterol and lipoprotein(a)than ideal weight children(P<0.05).Multiple linear regression analysis revealed that BMI was positive correlation with systo lic pressure,fasting insulin and triglyceride,and negative correlation with HDL.ConclusionCardiovascular and cerebrovascular disease factors were higher in malnutr ition and overweight children than ideal weight children.