Abstract: ObjectiveTo introduce how to do the principal component regression analysis with SPSS.MethodsThe analysis steps of the principal component regression by combining the Linear Regression,Factor Analysis,Compute Variable and Bivariate Correclations procedures in SPSS 8.0 for Windows with the basic principles of the principal component regression are introduced.ResultsAn example is used to describe all operations of each procedures in SPSS8.0 and all calculating processes of principal component regression,and the "best" equation is built.Conclusions The each indexes of multicollinearity diagnosis and the advantage and the point for attention about principal component regression analysis are introduced,and the simplified,speeded up and accurate statistical effect are reached through the prinicipal component regression analysis with SPSS.