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汪春红, 谭晓东, 王福元, 毕勇毅, 闫俊, 陶宁. 接触二硫化碳工人辨色错误得分水平及尿代谢物含量分析[J]. 中国公共卫生, 2001, 17(9): 779-781. DOI: 10.11847/zgggws2001-17-09-07
引用本文: 汪春红, 谭晓东, 王福元, 毕勇毅, 闫俊, 陶宁. 接触二硫化碳工人辨色错误得分水平及尿代谢物含量分析[J]. 中国公共卫生, 2001, 17(9): 779-781. DOI: 10.11847/zgggws2001-17-09-07
WANG Chun-hong, . Color Discrimination and Urinary Metabolites among the Workers Exposed to Carbon Disulfide[J]. Chinese Journal of Public Health, 2001, 17(9): 779-781. DOI: 10.11847/zgggws2001-17-09-07
Citation: WANG Chun-hong, . Color Discrimination and Urinary Metabolites among the Workers Exposed to Carbon Disulfide[J]. Chinese Journal of Public Health, 2001, 17(9): 779-781. DOI: 10.11847/zgggws2001-17-09-07

接触二硫化碳工人辨色错误得分水平及尿代谢物含量分析

Color Discrimination and Urinary Metabolites among the Workers Exposed to Carbon Disulfide

  • 摘要: 目的 为探讨长期接触CS2工人色觉功能及尿2.硫代塞唑烷.4.羧酸(TTCA)水平.方法 应用FM100.HUE方法检测工人辨色能力,高效液相色谱测定工人班末尿中TTCA含量.结果 CS2暴露组接触CS2时间加权平均浓度为15.53±6.29mg/m3.常规眼科检查未见特异损伤;FM100.HUE检查男、女工主要在5年~工龄段总错误得分水平、绿色及蓝色区带得分水平均显着高于同工龄段对照组(P<0.05).暴露组女工尿TTCA含量低于男工(P<0.01);15年工龄以上工人尿TTCA含量显着增高;10~15年工龄段男工尿TTCA含量与绿色区带的错误得分水平有一定相关性(P<0.05).结论 CS2对作业工人辨色力有一定影响,提示FM100.HUE辩色检查可作为低浓度CS2对视觉系统毒作用敏感的健康监测指标.

     

    Abstract: Objective To explore color vision effect CS2 and urinary metabolites on exposed workers.Methods The Color discrimination of the subjects was deter mined by the Far nsworth Munsell 100-HUE test(FM100-HUE).Urinary excretion of 2 -thio-thiazolidine-4-carboxilic acid(TTCA)in wor kers by the end of work shift was analyzed with modified high-performance liquid chromatography.Results(1)The FM100-HUE color vision score did occurred sig nificantly more often in the exposed group than among the referents,the discr imination to the green and blue zone were also impaired significantly(P<0.01).(2)In CS2 group,urinary TTCA of men was higher than that of women.The discr imination to the green zone was decline with the increas of TTCA excretion from 10 to 15 years to exposed CS2.Conclusion The color vision was disturbed in workers exposed to CS2,the FM100-HUE can be used as a sensitive indicator for the color vision effects of carbon disulfide.

     

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