Abstract: Objective To screen the risk factors for very early pregnant loss of females wor kers exposed to carbon disuphide (CS₂).Methods Non-conditional Logistic Regression Analysis was used to detect 30 factors collected in the prosepctive cohort study.Results It was showed that the main factors that enhanced the very pregnant loss were the exposure of CS₂ for women(P= 0.041 4),subjectively self-percept ible strains(P=0.070 1),and expourse of CS₂ for husbands(P=0.174 0).Having the experience of contraception of menorrhalgic,very early pregnant loss would become lower(P value were 0.103 5,0.184 0 respectively).Conclusion It was shown that women exposure to CS₂ was the main factors for very early pregnant loss and strains would promote the prequency of very early pregnant loss.