Abstract: ObjectiveTo study the relationship between occupational stress and hypertension,and to identify the main causing factors.MethodsA case-control study with 1:2 pairs was conducted with the application of occupational stress indication(OSI)among 96 train attendants with hypertension,then conditional logistic regression model analysis was used.ResultsIt was shown that independent joint action appeared to be existed between occupational stress and hypertension(OR= 2.531,P<0.01),and with a dose-effect pattern,when non-occupational stress factors were controlled.The main occupational stress factors causing hypertentension seemed to be the professional features(OR=2.608,P<0.01).ConclusionOccupational stress would be one of the important dangerous factors causing hypertension among train attendants,the main occupational stress factors causing hypertentension seemed to be the professional features.