Abstract: ObjectiveTo study the incidence and risk factors of pesticde mixtures poisoning,and raise a preventive plan for reducing the morbidity of pesticide mixtures poisoning.MethodsThose 1 102 pesticide mixtures sprayers(exposure group)and 1 260 single pesticide sprayers(control group)were investigated by means of epidemiologic methods.ResultsThe incidence of exposure group was sig nificantly higher than that of control group(P<0.05),the differences of the AchE inhibiting rate before or after spraying were no significance between exposure group and control group.Ten indexes,such as the spraying quantity and ways of pesticide using were the main risk factors causing pesticide poisoning.ConclusionThe risk exposing to pesticide mixtures was 4.5 times higher than that of single pesticide.Preventive measurements were raised.