肝癌高发区594例HBsAg阳性者3年随访情况研究

Three-year Follow-up Study on 594 HBsAg Positive Serum Samples from High Prevalent Area of Liver Cancer

摘要: 目的了解同安地区HBsAg阳性者3年后的乙型肝炎病毒感染标志的分布,HBV、HCV和HEV的感染情况及相互关系,AFP的阳性率.方法采用ELISA法检测594人的HBV、HCV和HEV感染标志及AFP.结果 HBsAg阳性率降为86.36%,但阳性者具有较强的传染性,HBV、HCV和HEV的感染者分别占人群的99.16%、0.84%和10.77%,AFP的阳性率为21885/10万.结论 HBV是AFP的危险因素,HCV和HEV的感染率低于全国水平.

Abstract: Objective Five hundred and ninety four HBsAg positive serum samples from Tongan area were followed up for three years to study the distribution of HBV infection markers,the infection situation and relationship of HBV,HCV and HEV,positive rate of AFP.Methods Five hundred and ninety four HBsAg positive serum sapmles were tested for HBV in2 fection markers,anti-HCV,anti-HEV and AFP by EL ISA.Results Positive rate of HBsAg declined to 86.36%,but HB2 sAg positive cases had more strong infectivity.The infection rate of HBV,HCV and HEV were 99.16%,0.84% and 10.77%,positive rate of AFP was 2 188.5/105.Conclusion HBV was risk factor for AFP.The infection rates of HCV and HEV were lower than the average of our country.