Abstract: Objective To approach the effect ing factors of anemia in late pregnancy.Methods The data are from 104 pregnant women.The independent variables of logistic regression model are serum ferritin(SF),free erythrocyte protoporphyrin (FEP),red cell distribution width(RDW),mean corpuscular volume(MCV)of middle pregnancy.The dependent variable is anemia in late pregnancy.Results Only FEP has a significant effect on anemia in late pregnancy(P<0.001).The partial regression coefficient is 12.048.The total per centage of expected anemia classification of logistic regression analysis consistent with the oberved classification is 89.4%,which is satisfactory.Whereas RDW,SF and MCV don'thave a significant effect on anemia in late pregnancy(P>0.05).Conclusion Free erythocyte protoporphyrin(FEP)in middle pregnancy has a significant effect on anemia in late pregnancy.