密闭空调环境对人体体液免疫和细胞免疫水平的影响

Effects of Enclosed Air-Condition Room on Humoral Immune and Celluar Immune

摘要: 目的探讨在密闭空调环境下工作的人群体液免疫和细胞免疫水平的变化。方法用免疫球蛋白测定试剂盒测定人体血清中IgG、IgA、IgM,用酶免定量测定试剂盒测定人体血清中的IgE,应用APAAP法测定外周血T淋巴细胞亚群。结果在密闭空调下工作的人群血清中IgG、IgE、IgM水平以及外周血T淋巴细胞亚群CD₈⁺、CD₈⁺、CD₈⁺/CD₈⁺呈下降趋势,而CD₈⁺则升高,与对照组比较,IgM、CD₈⁺、CD₈⁺、CD₈⁺/CD₈⁺两者的差异具有非常显着性意义(P<0.01).结论长期在密闭空调环境下工作可引起人体免疫功能下降,使人体更容易受到细菌病毒感染。

Abstract: Objective To study the change of human humoral and cellular immune under enclosed air-condition room.Methods IgG、IgA、IgM、IgE in serum were dectected by immune g lobins detection kits and the subgroups of T immune cell detected by APAAP methods.Results The levels of IgG、IgE、IgM,CD₃⁺、CD₄⁺、CD₄⁺/CD₈⁺ of the group in air-condition room declined,but CD₈⁺ rose.Compared with the normal control group,the difference of IgM、CD₄⁺、CD₈⁺、CD₄⁺/CD₈⁺ were significant(P<0.01).Conclusion The function of immune may decline as people working in the enclosed air-condition room for long time.