Abstract: Objective To find out usage behaviors and knowledge of antibiotics in community population and to study the possibility of antibiotics using intervention with medicine education in communities.Methods An intervention of medicine education to one community population was carried out.Results The intervention of medicine education to community population had sig nificant effects on the seeking of medicine advice on patients.behaviors when the drug was invalid,on the time of taking in drugs or stopping them.The sources and prices of antibiotics,the basis of antibiotics selected,how to take in drugs and the higher prices of antibiotics were not significantly affected by the intervention.The average income of patients also played an important role in seeking medicine and antibiotics usage.How to seek medicine,behaviors after no drug affection and time of taking in drugs were significantly enhanced in the lower income population,but these factors were not so high in the higher income population as their pre-intervention correct selecting was much higher.The time of stopping drugs after the disease sy mptom had lost was not affected in the lower income population but was significantly cared in the higher income population.Conclusion Medical educat ion to community population could significantly change their way of seeking medicines and antibiotics usage.