高级检索
王仪, 潘恩春, 张广, 杨文洲, 胡旭, 开海涛. 食管癌高发地区高危人群筛查方法研究[J]. 中国公共卫生, 2005, 21(7): 775-777. DOI: 10.11847/zgggws2005-21-07-03
引用本文: 王仪, 潘恩春, 张广, 杨文洲, 胡旭, 开海涛. 食管癌高发地区高危人群筛查方法研究[J]. 中国公共卫生, 2005, 21(7): 775-777. DOI: 10.11847/zgggws2005-21-07-03
WANG Yi, PAN Enchun, ZHANG Guang, . Method study on screening for neoplasm of esophagus among high risk population[J]. Chinese Journal of Public Health, 2005, 21(7): 775-777. DOI: 10.11847/zgggws2005-21-07-03
Citation: WANG Yi, PAN Enchun, ZHANG Guang, . Method study on screening for neoplasm of esophagus among high risk population[J]. Chinese Journal of Public Health, 2005, 21(7): 775-777. DOI: 10.11847/zgggws2005-21-07-03

食管癌高发地区高危人群筛查方法研究

Method study on screening for neoplasm of esophagus among high risk population

  • 摘要:
      目的   建立食管癌高危筛查模型, 浓缩筛查高危人群, 提高筛查效率。
      方法   通过对222对病例和对照进行1:1配对研究, 寻找与食管癌发病关联的因素, 利用判别分析和综合评价分析, 建立食管癌筛查模型, 选择指标建立判别方程, 用隐血珠筛查结果和由模型所得的个体食管癌发生的后验概率进行验证, 并结合现场实践进行判定。
      结果   多因素条件Logistic回归分析显示, 急躁型情绪类型、食用酱菜和盐腌制品频次、喜食辣食情况、有喜欢吃硬食、粗粮的习惯、近阶段是否明显消瘦、有癌症家族史为食管癌关联指标。隐血珠筛查阳性者食管癌的检出率可从3.01%提高到8.74%。
      结论   食管癌的发病与诸多不良的生活习惯与行为有关, 这不仅为食管癌病因学预防提供依据, 也为食管癌早期发现、早期诊断和早期治疗中的初级筛查提供建立模型的可能。

     

    Abstract:
      Objective   To build an assessment model about the risk for neoplasm of esophag us by the association between the harmful life style and neo plasm of esophagus and to enhance screening efficiency.
      Methods   To find the relevant risk factors through case control study including 222 cases and control group with a ratio of 1 to 1, and to build risk assessment model for neoplasm of esophagus by discriminant analysis.
      Results   Multivariate lo gistic analysis showed that the relative factors were the types of emotion, over intake of pickle food, habit of eating spicy food and eating stiff food, recent tendency of be coming thinner, family history.Some significant variables were selected to set up the screening model.The rate of screening for neoplasm of esophagus was enhanced from 3.01% to 8 74%.
      Conclusion   Neoplasm of esophagus was relevant to many harmful life styles.Not only it could provided the evidences for primary prevention of neoplasm of esophag us, but also it made the screening model of secondary prevention possible.

     

/

返回文章
返回