Abstract:
Objective To identify prognostic factors in patients with esophageal cancer after curative resection.
Methods 971 patients operated on for neoplasia of the esophagus, who underwent a curative resection were included in this study.14 variables were studied by univariate analysis.The variables linked with survival were include in a Cox model and then prognostic index(PI)was calculated.Cumulative surviva of the entire population was computed by Life table analysis.
Results Cumulative survival at 3 and 5 years was 78.29%, 68.81%, respectively and median survival was 97149 months.In univariate analysis, 10 out of 14 factors were statistically linked with survival.In multivariate analysis(Cox model), 5 independent factors were linked with survival which included:clinical stage, location of tumor, differentiation of tumor, depth of invasion and number of node metastases.
Conclusion Cumulative survival at 3, 5 years was relatively high.According to the Wald value, clinical stage was the major prognostic factor affecting the survival of patients with esophageal carcinoma.
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