马鞍山市志贺菌福氏4c亚型毒力基因分布

Investigation on verulence gene of Shigella F4c subtype in Ma’anshan

摘要: 目的了解马鞍山地区志贺菌福氏4c亚型感染株毒力分布特点,分析其流行模式。方法应用PCR技术,检测48株志贺菌福氏4c亚型菌株的ipaH,ial、set、sen等4种毒力基因。结果 ipaHi、als、ets、en等4种毒力基因在48株志贺菌福氏4c亚型的分布分别为100%98%,96%,88%;其毒力基因模式主要分成5型,其中Ⅰ型是本地区主要流行模式。结论马鞍山地区志贺菌福氏4c亚型普遍携带ipaHials、et、sen等4种毒力基因;毒力强、感染力强是该血清型成为本地主要流行型别的主要原因。

Abstract: Objective To investigate ipaH、ial、Set、sen verulence gene surveillance among the Shigella F4c strains from Macanshan,Anhui province and epidemic type.Methods PCR was used to detect ipaH,ial,set,sen verulence gene.Results The distribution of ipaH,ial,set,sen verulence gene among these 48 strains was seperatelly 100%,98%,96%,88%;These strains can be classified into 5 types.Type I was main in this area.Conclusion The PCR results showed the ipaH、set、sen verulence gene were generally present among these strains.The presence of ipaH、ial,set、sell verulenee gene made this type spread in this region.