河南省实施HIV母婴传播干预措施效果分析
Analysis on efficacy of intervention on mother to child transmission of HIV in Henan province
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摘要: 目的 了解实施艾滋病母婴传播干预措施对人类免疫缺陷病毒(HIV)母婴传播的影响。方法 对河南省31个重点县HIV阳性孕产妇及所生婴幼儿干预状况进行调查。调查新生儿出生时服药情况、喂养方式及其母亲的分娩方式、服用抗病毒药物等情况,比较服药组与未服药组幼儿人类免疫缺陷病毒(HIV)阳性率的差异。结果 实施药物阻断组艾滋病母婴传播率为3.45%,未实施药物阻断组的母婴传播率为15.38%,2组间差异有统计学意义,P<0.01。阳性产妇实施药物阻断措施后,自然分娩方式HIV传播率明显低于剖宫产方式的传播率。结论 对阳性孕产妇新生儿及时服用抗病毒药物并对婴儿实施纯人工喂养等措施,可有效降低HIV母婴传播率。建议在实施母婴传播干预措施的地区,不主张将HIV抗体阳性作为剖宫产的指征,最好选择自然分娩方式。Abstract: Objective To know how prevention works on HIV mother-to-child transmission.Methods A survey was conducted to study the children with HIV+mothers including children's medication taking after birth,feeding method,delivery method and ART for mothers to prevent mother-to-child transmission.Chi-square tests was implemented to see if children's infection rate differed between intervention group and control group.Results The infection rate of intervention group was 3.45%,while that of the control group was 15.38%.There was significant difference between these two groups.Conclusion Timely ART on pregnant mothers and their babies,intervention on artificial feeding,can effectively reduce HIV mother-to-child transmission rate.
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