Abstract: Objective In order to understand the life satisfaction of differ ent period of suicide attempt and compare them between suicide attempters and paired controls to explore the effect of life satisfaction on suicide attempt.Methods A paired case-control study was car ried out with 220 suicide attempters who were gotten from depar tments of emergency or internal medicine of hospitals.The controls were selected from patients with other diseases or healthy persons who were in the same district,gender and age(within 3yrs)by 1:1 matching.And the controls were required not having history of suicidal behavior.The questionnaire including life satisfaction was referenced to multicenter intervention study on suicide behavior of World Health Organization.L ife satisfactio n was scaled from very satisfaction equal to 1 to very dissatisfaction equal to 5.The different periods of life satisfaction were now,1 year after,5 years after,1 month before,1 year before,5 years before.Results During different periods of life satisfaction of suicide attempt,there were highest score in the period of suicide attempt time,its mean and standard deviation were 3.24 and 0.91 and the lowest score in the period of 5 years before suicide time,its mean and standard were 2.70 and 0.82.Single variable conditional logistic regression model showed that life satisfactions of different periods of suicide attempt were all significantly associated with suicide attempt and the Odds Ratios(95%CI)were followed as below:life dissatisfaction of suicide attempt time being 5.75(95%CI:3.11~10.61),one month before being 6.0 (95%CI:3.17~11.36),one year before being 6.14(95%CI:2.76~13.66),five years before being 2.27(95%CI:1.12 ~4.62),one year after being 5.11(95%CI:2.50~10.44),five years after being 7.33(95%CI:3.12~17.21).Conclusion Life dissatisfaction,especially life dissatisfaction of one month before and suicide attempt time might play a certain role in suicide attempt.