高级检索
马瑞, 许国章, 董红军, 边国林, 倪红霞, 周绍英. 宁波市母婴麻疹抗体水平及相互关系[J]. 中国公共卫生, 2008, 24(6): 747-748. DOI: 10.11847/zgggws2008-24-06-62
引用本文: 马瑞, 许国章, 董红军, 边国林, 倪红霞, 周绍英. 宁波市母婴麻疹抗体水平及相互关系[J]. 中国公共卫生, 2008, 24(6): 747-748. DOI: 10.11847/zgggws2008-24-06-62
MA Rui, XU Guo-zhang, Dong Hong-jun, . Maternal-infant pairs comparative study on the change of maternal transferred measles antibody level in infants[J]. Chinese Journal of Public Health, 2008, 24(6): 747-748. DOI: 10.11847/zgggws2008-24-06-62
Citation: MA Rui, XU Guo-zhang, Dong Hong-jun, . Maternal-infant pairs comparative study on the change of maternal transferred measles antibody level in infants[J]. Chinese Journal of Public Health, 2008, 24(6): 747-748. DOI: 10.11847/zgggws2008-24-06-62

宁波市母婴麻疹抗体水平及相互关系

Maternal-infant pairs comparative study on the change of maternal transferred measles antibody level in infants

  • 摘要: 目的 了解浙江省宁波市母婴麻疹抗体水平及婴儿母传抗体衰减情况,为探讨降低小月龄婴儿麻疹发病率制订免疫措施。方法 在宁波市余姚、象山县选取0,3,6,8和9月龄未患过麻疹的本地常住婴儿及母亲作为研究对象,采用酶联免疫吸附法(ELISA)检测IgG抗体。结果 婴儿出生时麻疹抗体阳性率为91.0%,几何平均滴度倒数(GMRT)为890.18。6和8月龄时抗体阳性率只有4.1%,0.8%,GMRT分别为4.17,1.59。婴儿麻疹抗体水平与母亲抗体水平的相关系数为0.769,表明婴儿抗体有无及水平与母亲抗体水平有密切关系。结论 6,8月龄婴儿抗体阳性率及抗体水平均很低,几乎无保护作用;降低小月龄麻疹发病,必要时应对6月龄婴儿实行初免以提高保护率,同时提高育龄期妇女麻疹抗体水平。

     

    Abstract: Objective To draw relative immunity policies of reducing infant measles through analyzing antibody level of comparison in maternal-infant pairs and the change in infants.Methods Newborn,3-month,6-month,8-month,9month infants who never had measles and their mothers who were resident in Yuyao,Xiangshan were collected as subjects.Their serum samples were measured by the method of EL ISA.Results The positive rate and GRM T of measles antibody in newborns were 91.0 percent and 890.18,respectively,which reduced to 4.1 percent and 4.17 till 6 months,0.8 percent and 1.59 at 8 months.There was a close correlation between maternal measles antibody level and newborns',the correlation coefficient was 0.769.Conclusion Maternal-transferred measles antibody decreased as the growth of infant.The positive rate of measles antibody is very low in 6-month and 8-month,which makes almost no protection.In order to control infant measles,it's necessary for infant to be vaccinated at 6 months and for the women's measles antibody level to be increased by vaccination at the same time.

     

/

返回文章
返回