Abstract: Objective To study H5 and H9 infection of different kinds of poultry workers in Guangzhou city.Methods The blood samples of the poultry retailing workers in food markets and poultry br eeding workers in large scale enter prises and rural individual farms were collected,and micro-hemag glutination inhibition test was used to detect antibodies of H5 and H9.Results 369 blood samples of poultry wor kers were sur veyed.The H9 antibody positive rate of retailers in food markets (16146%,13/79)was higher than that of the feeders in individual farms(3.40%,5/147),and also higher than that of the feeders in large scale enter prises(4.90%,7/143).The H9 antibody positive rate of the feeders in individual farms was indistinctive with the feeders in large scale enterprises.No H5 positive antibody was deteced.Conclusion There is a higher risk of avian influenza infection among poultry retailing workers than that of poultry workers in large scale enter prises and rural individual farms.