Abstract: Objective To explore the relationship between spiritual belief and subjective sense of happiness among middle school students.Methods A total of 764 middle school students in Baotou city,Inner Mongolia were investigated with a questionnaire of spiritual belief and happiness.Results The scores of supernatural belief,social belief,practical belief were 2.38±0.79,3.86±0.63,and 2.93±0.60,respectively,for the students.There was a notable relationship between supernatural belief,social belief and sense of happiness.Supernatural belief showed notable negative function for the prediction of emotion index and sense of happiness index (Beta=0.092 0.104,t=2.8743.373,P < 0.01).But social belief showed obvious positive function for the prediction of emotion index,degree of life saisfaction and happiness index (Beta=0.2070.248,t=5.8327.071,P < 0.001).The second level of dmiension of spiritual belief showed different functions for the prediction of subjective sense of happiness.Conclusion Spiritual belief has an effect on the subjective sense of happiness among middle school students.