Abstract: Objective To study the job satisfaction and its main influencing factors amongente rprise employees.Methods Across-sectional survey was implemented on September 2010.Totally 1000 employees were randomly selected as the study population from an enterprise in Shenyang.Job satisfaction was measured with Minnesota Satisfaction Questionnaire(MSQ) and occupational stresswasmea sured with Effort reward Imbalance Questionnaire (ERI) and perceived organizational support was measured with Survey of Perceived Organizational Support(POS).Ahie rarchical regression analysis was used to analyze the factors influencing job satisfaction.Results The overall average score of employees satisfaction was 63.81±11.44.Hierarchical regression revea led that the contributions of working condition,occupational stress,and organizational support to job satisfaction were 15.7%,9.9%,and 8.6%,respectirely.Conclusion The overall satisfaction of the employees is not high and the main a ffecting factors are working condition,occupational stress and organizational support.