Abstract: Objective To develop a psychological and physical questionnaire for hypertensive and to evaluate its validity and reliability.Methods The self-esteem structures were formed by analyses of literature,questionnaire survey and interview among hypertension patients.A total of 403 hypertension patients were asked to complete the questionnaire.The data were analyzed with project analysis,exploratory factor analysis,and reliability and validity tests.Results The questionnaire was finally refined as a list of 36 items on four dimensions,including mental function,social function,physical function and habits,with a cumulative contribution rate of 45.568%.The test-retest coefficients for the four dimensions and the total score was 0.762,0.739,0.792,0.660,and 0.786 and the values of Cronbach α was 0.834,0.846,0.771,0.662,and 0.921,respectively.The split-half reliability for the questionnaire was 0.904.The content validities for the four dimensions were 0.678,0.739,0.784,and 0.690(P< 0.01 for all).The questionnaire had high validity and reliability.Conclusion The psychological and physical questionnaire for hypertensive was developed and the questionnaire has high validity and reliability.