Abstract: To explore different sub-health status between populations of different gender.MethodsA cross-sectional study was conducted to analyze sub-health status of 13 439 people in 8 provinces in China.ResultsSubhealth status of male was much more expressed in sexual life(male:5.22±1.06,femal:4.92±0.96),while female was much more expressed in physical and psychological symptoms(physical symptoms score for male:104.53±20.47,for female:110.27±20.90;psychological score for male:53.63±8.04,for female:55.89±7.88;P<0.01).Social adaptability showed no significant gender difference(P>0.05).For somatic symptoms,the men had a hypo-immunity and were susceptible to cold or with a longer period of the disease compared to the woman(P<0.001).While women felt tired easily and frequently had digestive problem,poor sleep,autonomic nervous disorders,allergy,aging apperance,a variety of pain or discomfort,constipation,and frequent drug usage(P<0.001).In psychological symptoms,women showed more depression, anxiety problem,memory loss,and severe stress than men(P<0.001 for all).There was a significant difference in sexual satisfaction score between the men and the women with sub-health(P<0.01)and the men were more likely to worry about sexuality than women(P<0.01).ConclusionThe symptoms of sub-health are different between men and women in Chinese population.