Abstract: ObjectiveTo analyze the association of hip circumference(HC)with metabolic syndrome(MS)and to provide evidence for etiologic study and prevention of the disease.MethodsWith cluster-sampling method,a total of 2 589 Mongolian people in Tongliao city of Inner Mongolia were included in the study.Demographic data was collected;anthropometric indices and blood pressure were measured according to standard protocol.Biochemical analysis was conducted on fasting blood samples.Multinomial logistic regression was adopted to analyze the association of HC with MS.ResultsBinary logistic regression show ed that after adjustment for age,gender,smoking,drinking,history of hypertension,body mass index (BMI),and C-reative protein(CRP),successive quartiles of HC were positively associated with MS,with the odds ratios (ORs)and 95% confidence interval(95% CI)of 1.000,2.365(1.299-4.307),5.777(3.302-10.107),and 12.594 (7.008-22.630)for the residents with the HC of<88 cm,88-91 cm,92-96 cm,and≥97 cm,respectively,and a doseresponse relationship(trend test:P<0.001).Multinomial logistic regression show ed positive association of HC with MS after adjustment for age,gender,BMI,and CRP.compared to that of residents with the low est quartile of HC,the OR for the residents with 1-2 components of MS were 1.191(0.884-1.605),1.709(1.232-2.370),and 2.646(1.538-4.551) and those for the residents with≥3 components of MS were 2.112(1.332-3.349),4.910(3.084-7.820),and 10.931 (5.746-20.796)for the HC quartiles of 88-91 cm,92-96 cm,and≥97 cm,respectively,with dose-response relationships(trend test:P<0.001 for all).ConclusionHigh hip circumference was associated with a higher risk of MS among Mongolian residents in Inner Mongolia.