Abstract: ObjectiveTo explore behavioral changes related to human immunodeficieny virus/acquired immunodeficiency syndrome(HIV/AIDS)and trends of HIV/syphilis epidemic among female sex workers(FSWs)in Fengtai district, and to provide information for integrated HIV behavioral intervention.MethodsContinuous HIV antibody test and syphilis rapid plasma region test were conducted among FSWs in Fengtai district of Beijing from 2006 to 2009.At the same time,the FSWs workers were interviewed face-to-face with an anonymous questionnaire.ResultsThe prevalence rate of HIV infection was 0 in the FSWs in community and 0.4%,0.4%,0,and 0 in the FSWs in other places from 2006 to 2009,respectively.The prevalence rate of syphilis was 3.0%,2.1%,1.5%,and 1.0% in the FSWs in community and 8.6%,10.4%, 6.4%,and 3.8% in the FSWs in other places from 2006 to 2009,respectively.The rate of using condom in the last commercial sex among the FSWs in community was 94.0%,88.5%,92.3%,and 94.7% and 79.0%,88.0%,88.5%,and 91.7% in the FSWs in other places from 2006-2009,respectively.ConclusionRate of condom use among the FSWs in Fengtai district tend to increase and HIV prevalence rate is generally low.However,HIV knowledge and testing awareness need to be enhanced.The FSWs in small public places is the key population for effective intervention.